| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
Effect of an Arctium lappa (burdock) extract on the labeling of blood constituents with technetium-99m and on the morphology of the red blood cells
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| Autores: |
Neves,Rosane de Figueiredo
Moreno,Silvana Ramos Farias
Rebello,Bernardo Machado
Caldas,Luiz Querino de Araújo
Fonseca,Adenilson de Souza da
Bernardo-Filho,Mario
Medeiros,Aldo da Cunha
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| Data: |
2007-09-01
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| Ano: |
2007
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| Palavras-chave: |
Arctium lappa
Technetium-99m
Blood constituents
Morphometry
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| Resumo: |
Arctium lappa (burdock) has been used to treat inflammatory processes. Blood constituents labeled with technetium-99m (99mTc) have been utilized in nuclear medicine. It was evaluated the influence of a burdock extract on the labeling of blood constituents with 99mTc and on the morphometry of red blood cells. Blood samples from Wistar rats were incubated with burdock extract and the radiolabeling procedure was carried out. Plasma and blood cells, soluble and insoluble fractions of plasma and blood cells were separated. The radioactivity in each fraction was counted and the percentages of radioactivity (%ATI) were determined. Morphology and morphometric (perimeter/area ratio) measurements of red blood cells (RBC) were performed. The incubation with burdock extract significantly (p<0.05) altered the %ATI on the blood compartments and the perimeter/area ratio of RBC, as well as, induced modifications on the shape of RBC. Alterations on membrane could justify the decrease of labeling of blood cells with 99mTc obtained in this study.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000600021
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/S1516-89132007000600021
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.50 n.spe 2007
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| Direitos: |
info:eu-repo/semantics/openAccess
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